Theracurmin HP
$56.00
- SKU:
- IT-10630
- UPC:
- 871791106307
Integrative Therapeutics Theracurmin HPis a novel preparation of turmeric that utilizes patented, colloidal dispersion technology to enhance bioavailability and dramatically increase curcumin levels in the blood - See details
Integrative Therapeutics Theracurmin HP
Integrative Therapeutics uses Theracumin HP is an enhanced bioavailability water-dispersible turmeric rhizome complex made through patented colloidal dispersion technology, in its Theracurmin HP. This allows the curcumin to dissolve quickly and maintain its solubility over time. Considering that most standard curcumin extracts are poorly absorbed in high doses, this is a great breakthrough. This is a triple-strength formula, which allows you to take just two smaller capsules per day.
Product Information:
- Source of curcuminoids
- 27x more bioavailable than standard curcumin extracts
- May relieve occasional pain due to overuse
- May support the body's natural detoxification pathways
- Take just two capsules per day
- Vegetarian
This supplement is often used to temporarily relieve occasional pain from overuse, to support detox pathways and cytokine response, and more. It is free of wheat, gluten, soy, yeast, salt, dairy products, ingredients of animal origin, and artificial colors, flavors, and preservatives.
Biological Effects of Curcumin
For over more than three decades, in vitro and in vivo research demonstrates that curcumin supports detoxification and cytokine pathways. While mechanisms of action are still under investigation, the chemical structure of curcumin directly influences antioxidant pathways, with its phenolic hydroxyl group behaving as an electron donor. Based on in vitro and in vivo studies, curcumin's indirect effects on antioxidant pathways include modulating cellular redox homeostasis and enhancing the activity of antioxidant enzymes like catalase, superoxide dismutase, Glutathioneperoxidase, and glutathione-S-transferase, enzymes that also support detoxification and cytokine pathways.
Benefits of Theracurmin
The benefits of Theracurmin® have been demonstrated in several clinical studies. Theracurmin® has been shown to:
SUPPORT LIVER DETOXIFICATION PATHWAYS*
In a small placebo-controlled crossover study evaluating the effect of Theracurmin® on liver function, healthy subjects (N=7) were given either a single oral administration of 30 mg of
Theracurmin or placebo along with alcohol on alternating days.1 Theracurmin® reduced blood acetaldehyde concentrations after compared to placebo, supporting a liver detoxification effect of
Theracurmin.*
SUPPORT HEALTHY CARDIOVASCULAR FUNCTION*
In a three-arm clinical study evaluating flow-mediated dilation as an indicator of healthy endothelial function, healthy postmenopausal women (N=10-11 per group) were administered 150 mg/d Theracurmin®, an aerobic exercise regimen or no intervention (control).3 Both 150 mg/d Theracurmin® and aerobic exercise groups had significantly increased flowmediated dilation compared to the control group; there was no significant difference between the Theracurmin® and aerobic exercise groups.* This result indicates a role for Theracurmin® in supporting healthy cardiovascular function.*
SUPPORT MUSCLE RECOVERY AFTER ACUTE EXERCISE*
In a small placebo-controlled crossover study evaluating the effect of Theracurmin® on muscle recovery, healthy, nonconditioned men (N=14) were administered either 150 mg Theracurmin® or placebo before and 12 hours after maximal biceps flexion exercise on alternating days.4 Theracurmin® administration resulted in a smaller change in maximal voluntary muscle contraction (an indicator of muscle recovery) four days post-exercise compared to placebo.* This result indicates a role for Theracurmin® in supporting muscle recovery after acute exercise.*
PROVIDE RELIEF OF MINOR PAIN DUE TO OCCASIONAL OVERUSE*
In a double-blind, placebo-controlled study, subjects (N=25 per group) were given either 180 mg/d Theracurmin® or placebo.5 Self-reported discomfort measured by Visual Analogue Scale was significantly reduced in subjects administered Theracurmin® compared to placebo.* This result indicates a role for Theracurm
Bioavailability of Curcumin
In spite of its broad spectrum of biological activities, the use of curcumin is challenging because of its chemical instability at intestinal pH levels, low water solubility, poor oral bioavailability, and rapid conjugation and excretion.8 This combination of factors makes it difficult for orally administered curcumin to promote its bioactivities. The challenge, therefore, has been to find a way to improve curcumin's bioavailability. Several strategies have been utilized to improve curcumin bioavailability including the use of adjuvants (i.e., piperine from black pepper), maximizing the lipophilic nature of curcumin through the use of liposomes, curcumin phospholipid complexes, and curcumin submicron and nanoparticles.9
Theracurmin is Over 27 Times More Bioavailable Than Standard Curcumin Extracts
Standard curcumin is poorly absorbed even at high doses. Human clinical trials show that Theracurmin® is over 27 times more bioavailable than a standard curcumin extract and is many times more bioavailable than other commercially-available curcumin supplements.*1,2 Theracurmin® has been clinically shown to support detoxification pathways, healthy cardiovascular function, muscle recovery after acute exercise, and provide relief of minor pain due to occasional overuse.*1,3-5
Recommended Use:
Adults: Take as recommended by your healthcare professional. A typical dose is 2 capsules or more once per day for 7 days; may reduce dosage to 1 capsule per day thereafter, or as recommended by your healthcare professional.
Warning:
If pregnant, nursing, or taking prescription drugs, consult your healthcare professional prior to use. Keep out of the reach of children.
References
1. Sasaki H et al. Biol Pharm Bull. 2011;34(5):660-5.
2. Sunagawa Y et al. J Nutr Sci Vitaminol. 2015;61:37-44.
3. Akazawa N et al. Nutr Res. 2012;32(10):797-9.
4. Tanabe Y et al. Eur J Appl Physiol. 2015;115(9):1949-57.
5. Nakagawa Y et al. J Orthop Sci. 2014;19:933-9.
6. Gupta SC et al. Clin Exp Pharmacol Physiol. 2012;39(3):283-99.
7. Xu XY et al. Nutrients. 2018;10:1553.
8. Lee WH et al. Curr Neuropharmacol. 2013;11(4):338-78.
9. Bisht S et al. Curr Drug Discov Technol. 2009;6(3):192-9
Disclaimer: These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.
Supplement Facts
2 capsules contain:
Total Carbohydrate <1 g <1%
Theracurmin 600mg
---(enhanced bioavailability water-dispersible turmeric (Curcuma longa) rhizome complex) providing 30% curcumin (180mg)
Other Ingredients: cellulose, maltose, hydroxypropyl methylcellulose (vegetable capsule), gum ghatti, ascorbyl palmitate, dextrin, citric acid, and silicon dioxide.
Contains NO: salt, yeast, wheat, gluten, soy, dairy products, artificial colors, artificial flavors, preservatives, or ingredients of animal origin.
Description
Integrative Therapeutics Theracurmin HP
Integrative Therapeutics uses Theracumin HP is an enhanced bioavailability water-dispersible turmeric rhizome complex made through patented colloidal dispersion technology, in its Theracurmin HP. This allows the curcumin to dissolve quickly and maintain its solubility over time. Considering that most standard curcumin extracts are poorly absorbed in high doses, this is a great breakthrough. This is a triple-strength formula, which allows you to take just two smaller capsules per day.
Product Information:
- Source of curcuminoids
- 27x more bioavailable than standard curcumin extracts
- May relieve occasional pain due to overuse
- May support the body's natural detoxification pathways
- Take just two capsules per day
- Vegetarian
This supplement is often used to temporarily relieve occasional pain from overuse, to support detox pathways and cytokine response, and more. It is free of wheat, gluten, soy, yeast, salt, dairy products, ingredients of animal origin, and artificial colors, flavors, and preservatives.
Biological Effects of Curcumin
For over more than three decades, in vitro and in vivo research demonstrates that curcumin supports detoxification and cytokine pathways. While mechanisms of action are still under investigation, the chemical structure of curcumin directly influences antioxidant pathways, with its phenolic hydroxyl group behaving as an electron donor. Based on in vitro and in vivo studies, curcumin's indirect effects on antioxidant pathways include modulating cellular redox homeostasis and enhancing the activity of antioxidant enzymes like catalase, superoxide dismutase, Glutathioneperoxidase, and glutathione-S-transferase, enzymes that also support detoxification and cytokine pathways.
Benefits of Theracurmin
The benefits of Theracurmin® have been demonstrated in several clinical studies. Theracurmin® has been shown to:
SUPPORT LIVER DETOXIFICATION PATHWAYS*
In a small placebo-controlled crossover study evaluating the effect of Theracurmin® on liver function, healthy subjects (N=7) were given either a single oral administration of 30 mg of
Theracurmin or placebo along with alcohol on alternating days.1 Theracurmin® reduced blood acetaldehyde concentrations after compared to placebo, supporting a liver detoxification effect of
Theracurmin.*
SUPPORT HEALTHY CARDIOVASCULAR FUNCTION*
In a three-arm clinical study evaluating flow-mediated dilation as an indicator of healthy endothelial function, healthy postmenopausal women (N=10-11 per group) were administered 150 mg/d Theracurmin®, an aerobic exercise regimen or no intervention (control).3 Both 150 mg/d Theracurmin® and aerobic exercise groups had significantly increased flowmediated dilation compared to the control group; there was no significant difference between the Theracurmin® and aerobic exercise groups.* This result indicates a role for Theracurmin® in supporting healthy cardiovascular function.*
SUPPORT MUSCLE RECOVERY AFTER ACUTE EXERCISE*
In a small placebo-controlled crossover study evaluating the effect of Theracurmin® on muscle recovery, healthy, nonconditioned men (N=14) were administered either 150 mg Theracurmin® or placebo before and 12 hours after maximal biceps flexion exercise on alternating days.4 Theracurmin® administration resulted in a smaller change in maximal voluntary muscle contraction (an indicator of muscle recovery) four days post-exercise compared to placebo.* This result indicates a role for Theracurmin® in supporting muscle recovery after acute exercise.*
PROVIDE RELIEF OF MINOR PAIN DUE TO OCCASIONAL OVERUSE*
In a double-blind, placebo-controlled study, subjects (N=25 per group) were given either 180 mg/d Theracurmin® or placebo.5 Self-reported discomfort measured by Visual Analogue Scale was significantly reduced in subjects administered Theracurmin® compared to placebo.* This result indicates a role for Theracurm
Bioavailability of Curcumin
In spite of its broad spectrum of biological activities, the use of curcumin is challenging because of its chemical instability at intestinal pH levels, low water solubility, poor oral bioavailability, and rapid conjugation and excretion.8 This combination of factors makes it difficult for orally administered curcumin to promote its bioactivities. The challenge, therefore, has been to find a way to improve curcumin's bioavailability. Several strategies have been utilized to improve curcumin bioavailability including the use of adjuvants (i.e., piperine from black pepper), maximizing the lipophilic nature of curcumin through the use of liposomes, curcumin phospholipid complexes, and curcumin submicron and nanoparticles.9
Theracurmin is Over 27 Times More Bioavailable Than Standard Curcumin Extracts
Standard curcumin is poorly absorbed even at high doses. Human clinical trials show that Theracurmin® is over 27 times more bioavailable than a standard curcumin extract and is many times more bioavailable than other commercially-available curcumin supplements.*1,2 Theracurmin® has been clinically shown to support detoxification pathways, healthy cardiovascular function, muscle recovery after acute exercise, and provide relief of minor pain due to occasional overuse.*1,3-5
Recommended Use:
Adults: Take as recommended by your healthcare professional. A typical dose is 2 capsules or more once per day for 7 days; may reduce dosage to 1 capsule per day thereafter, or as recommended by your healthcare professional.
Warning:
If pregnant, nursing, or taking prescription drugs, consult your healthcare professional prior to use. Keep out of the reach of children.
References
1. Sasaki H et al. Biol Pharm Bull. 2011;34(5):660-5.
2. Sunagawa Y et al. J Nutr Sci Vitaminol. 2015;61:37-44.
3. Akazawa N et al. Nutr Res. 2012;32(10):797-9.
4. Tanabe Y et al. Eur J Appl Physiol. 2015;115(9):1949-57.
5. Nakagawa Y et al. J Orthop Sci. 2014;19:933-9.
6. Gupta SC et al. Clin Exp Pharmacol Physiol. 2012;39(3):283-99.
7. Xu XY et al. Nutrients. 2018;10:1553.
8. Lee WH et al. Curr Neuropharmacol. 2013;11(4):338-78.
9. Bisht S et al. Curr Drug Discov Technol. 2009;6(3):192-9
Disclaimer: These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.
Ingredients
Supplement Facts
2 capsules contain:
Total Carbohydrate <1 g <1%
Theracurmin 600mg
---(enhanced bioavailability water-dispersible turmeric (Curcuma longa) rhizome complex) providing 30% curcumin (180mg)
Other Ingredients: cellulose, maltose, hydroxypropyl methylcellulose (vegetable capsule), gum ghatti, ascorbyl palmitate, dextrin, citric acid, and silicon dioxide.
Contains NO: salt, yeast, wheat, gluten, soy, dairy products, artificial colors, artificial flavors, preservatives, or ingredients of animal origin.