Nrf2 Detox
$61.80
- SKU:
- PE-NRF6
- UPC:
- 766298017624
Pure Encapsulations Nrf2 Detox is a three-ingredient detox formula designed to help stimulate detoxification and support antioxidant defenses - See details
Pure Encapsulations Nrf2 Detox - 60 Capsules
Nrf2 and detoxification support Cruciferous vegetables of the brassica family have long been recognized for their ability to support detoxification thereby maintaining healthy cells and tissues. Cruciferous vegetables, like broccoli, cauliflower, Brussels sprouts and kale, are the richest sources of glucosinolates, which are considered to be the most bioactive constituents. Glucosinolates are converted in the body to isothiocyanates after they are ingested and hydrolyzed.
The isothiocyanate sulforaphane is one of the most powerful activators of phase II enzyme function in the liver, supporting toxin elimination. Sulforaphane and resveratrol promote the activity of nuclear factor erythroid 2-related factor 2 (Nrf2), a transcription factor that supports the robust, long-lasting expression of numerous genes responsible for detoxification and protection against oxidative stress.
Among these genes are Glutathione peroxidase, superoxide dismutase and various phase II enzymes, such as glutathione sulfotransferases. Nrf2 also supports the expression of glutathione glutamylcysteinyl ligase, which is responsible for a critical step in the biosynthesis of glutathione, a vital component of cellular antioxidant and detoxification systems. Found in virtually every cell of the body, glutathione plays essential roles in protein synthesis, synthesis and repair of DNA, enzyme function, transport, and cell maturation.
Optimal levels of glutathione have been associated with physical and mental health. The highest concentration of glutathione is found in the liver, where it offers antioxidant support, protects tissue and maintains detoxification. In a randomized clinical trial, supplementation with 250 and 1,000mg of Setria glutathione per day increased glutathione levels in the blood after one, three and six months. At six months, mean glutathione levels in the high-dose group increased 30-35% in erythrocytes, plasma, and lymphocytes, and 260% in buccal cells (P<0.05). In the low-dose group, mean glutathione levels increased 17% and 29% in blood and erythrocytes, respectively (P<0.05). Both glutathione dose groups showed support for antioxidant defenses, indicated by decreases in the oxidized-to-reduced-glutathione ratio in whole blood after six months. Three-ingredient combination designed to support detoxification and antioxidant defenses.
- Supports phase II enzyme function in the gut and liver, supporting toxin elimination
- Promotes the activity of Nrf2 to support detoxification and protection against oxidative stress
- Bioavailable, clinically studied Setria glutathione
- Standardized to contain a minimum of 1,000 mcg sulforaphane
- Part of the PureGenomics product line
- Made with high-quality vegan ingredients backed by verifiable science
Recommended Use:
Adults: As a dietary supplement, take 1 capsule, 1-3 times daily, with meals.
Warning:
If you are pregnant, nursing, taking medications or have a medical condition, please consult your healthcare practitioner before use. Keep out of the reach of children.
Disclaimer: These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.
Supplement Facts
1 capsule contains:
Broccoli (Brassica oleracea italica) 250mg
---sprout concentrate (whole plant) (standardized to contain 1,000mcg sulforaphane)
Setria glutathione (reduced form) 250mg
resVida resveratrol (as trans-resveratrol) 15mg
Other Ingredients: vegetarian capsule (cellulose, water).
Contains NO: artificial additives, allergens, GMOs, environmental contaminants or added excipients.
Description
Pure Encapsulations Nrf2 Detox - 60 Capsules
Nrf2 and detoxification support Cruciferous vegetables of the brassica family have long been recognized for their ability to support detoxification thereby maintaining healthy cells and tissues. Cruciferous vegetables, like broccoli, cauliflower, Brussels sprouts and kale, are the richest sources of glucosinolates, which are considered to be the most bioactive constituents. Glucosinolates are converted in the body to isothiocyanates after they are ingested and hydrolyzed.
The isothiocyanate sulforaphane is one of the most powerful activators of phase II enzyme function in the liver, supporting toxin elimination. Sulforaphane and resveratrol promote the activity of nuclear factor erythroid 2-related factor 2 (Nrf2), a transcription factor that supports the robust, long-lasting expression of numerous genes responsible for detoxification and protection against oxidative stress.
Among these genes are Glutathione peroxidase, superoxide dismutase and various phase II enzymes, such as glutathione sulfotransferases. Nrf2 also supports the expression of glutathione glutamylcysteinyl ligase, which is responsible for a critical step in the biosynthesis of glutathione, a vital component of cellular antioxidant and detoxification systems. Found in virtually every cell of the body, glutathione plays essential roles in protein synthesis, synthesis and repair of DNA, enzyme function, transport, and cell maturation.
Optimal levels of glutathione have been associated with physical and mental health. The highest concentration of glutathione is found in the liver, where it offers antioxidant support, protects tissue and maintains detoxification. In a randomized clinical trial, supplementation with 250 and 1,000mg of Setria glutathione per day increased glutathione levels in the blood after one, three and six months. At six months, mean glutathione levels in the high-dose group increased 30-35% in erythrocytes, plasma, and lymphocytes, and 260% in buccal cells (P<0.05). In the low-dose group, mean glutathione levels increased 17% and 29% in blood and erythrocytes, respectively (P<0.05). Both glutathione dose groups showed support for antioxidant defenses, indicated by decreases in the oxidized-to-reduced-glutathione ratio in whole blood after six months. Three-ingredient combination designed to support detoxification and antioxidant defenses.
- Supports phase II enzyme function in the gut and liver, supporting toxin elimination
- Promotes the activity of Nrf2 to support detoxification and protection against oxidative stress
- Bioavailable, clinically studied Setria glutathione
- Standardized to contain a minimum of 1,000 mcg sulforaphane
- Part of the PureGenomics product line
- Made with high-quality vegan ingredients backed by verifiable science
Recommended Use:
Adults: As a dietary supplement, take 1 capsule, 1-3 times daily, with meals.
Warning:
If you are pregnant, nursing, taking medications or have a medical condition, please consult your healthcare practitioner before use. Keep out of the reach of children.
Disclaimer: These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.
Ingredients
Supplement Facts
1 capsule contains:
Broccoli (Brassica oleracea italica) 250mg
---sprout concentrate (whole plant) (standardized to contain 1,000mcg sulforaphane)
Setria glutathione (reduced form) 250mg
resVida resveratrol (as trans-resveratrol) 15mg
Other Ingredients: vegetarian capsule (cellulose, water).
Contains NO: artificial additives, allergens, GMOs, environmental contaminants or added excipients.